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Double-layered protein nanoparticles induce broad protection against divergent influenza A viruses

Layered nanoparticles are fabricated by desolvating tetrameric M2e into protein nanoparticle cores and coating these cores by crosslinking headless HAs. Recent advances in the applications of metabolomics in eye research. In vivo mechanical characterization of human facial skin combining curved surface imaging and indentation techniques.

We are testing a new system eli linking publications to authors. Formation of toxic polynitrophenols, nitrated biphenyls and diphenyl ethers.

Monoclonal antibody 14C2 was used as the coating antibody. Universal influenza vaccines, a dream to be realized soon.

Nurr1 promotes neurogenesis of dopaminergic neuron and represses inflammatory factors in the transwell 111684 system of neural stem cells and microglia.

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Characterization and comparative profiling of the small RNA transcriptomes in the Hemipteran insect Nilaparvata lugens. A promising approach is to express a standalone HA stalk domain without the highly immunogenic and strain-specific head domain, and a stabilized M2e with high epitope density. El Bakkouri K, et al.

Kanekiyo M, et al. Room-temperature ferromagnetism in TiO2 nanocrystals synthesized by the controlled hydrolysis procedure Journal of Nanoscience and Nanotechnology. In this study, we found that layered PNps composed of structure-stabilized HA stalk domains from both HA groups, and novel constructed M2e, are highly immunogenic to induce immune protection against homosubtypic and heterosubtypic influenza A virus challenges.

Journal of the Mechanical Behavior of Biomedical Materials. Ieee Transactions On Cybernetics.

Lei Zhou – Publications

Demento SL, et al. Tharakaraman K, et al. A systematic review and meta-analysis. K performed the experiments. Serum antibody response to matrix protein 2 following natural infection with pandemic influenza A H1N1 virus in humans. Cell Death and Differentiation.

Il sogno di Scipione by Pietro Metastasio

Biochimica Et Biophysica Acta. Hydraulic connectivity and evaporation control the water quality and sources of chromophoric dissolved organic matter in Lake Bosten in arid northwest China.

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Efficacy and safety of tacrolimus for myasthenia gravis: The power of tears: Therefore, the loop B truncation in hrH3 ended at the hydrophobic residue I77 to retain the most conserved regions. Coated protein nanoclusters from influenza H7N9 HA are highly immunogenic and induce robust protective immunity.

Th17 cells in autoimmune diseases. – Abstract – Europe PMC

A universal influenza A vaccine based on the extracellular domain of the M2 protein. Near-infrared rechargeable “optical battery” implant for irradiation-free photodynamic therapy. A label-free colorimetric biosensor for sensitive detection of vascular endothelial growth factor Inappropriateuse of FIB-4 index for cirrhosis detection in hepatocellular carcinoma patients.

PNp protective efficacy in mice. The P values were generated by analyzing data with a two-tail unpaired t test using the Prism 5 program GraphPad software.

Green tea polyphenol epigallocatechingallate alleviated coxsackievirus B3-induced myocarditis via inhibiting viral replication, but not through inhibiting inflammatory responses.