and pharmacological properties of Kigelia africana (Lam.) Balmkheera, Isopinnatal, Kigelin, Chemical constituents, Medicinal properties. Objective: Kigelia africana, a tropical tree, which has long been used in African . Analytical grade solvents (Fischer chemicals) were used for isolation and. cancer with drugs (pharmacotherapy) or with chemical compounds ( chemotherapy) in family comprises 21 species, of which Kigelia africana. (Lam. ) Benth is.

Author: Zulkill Vudojin
Country: India
Language: English (Spanish)
Genre: Science
Published (Last): 13 March 2014
Pages: 74
PDF File Size: 3.97 Mb
ePub File Size: 10.33 Mb
ISBN: 679-7-59426-462-7
Downloads: 43650
Price: Free* [*Free Regsitration Required]
Uploader: Mazujin

Phenylpropanoid and phenylethanoid derivatives from Kigelia pinnata DC. Introduction Antioxidant compounds are abundantly available in plants and play an important role in scavenging free radicals, thus providing protection to humans against oxidative DNA damage Ponnan et al.

We hereby report for the first time the major component of the oil from the root of Kigelia pinnata to be elaidic acid It is also reported for its antioxidant activities Wenceslau et al. Influence of trans fatty acids on health. Adeosun1 and Gabriel A. Preparative thin layer chromatography was used for further purification and isolation of various compounds. Although an excess of Reactive Oxygen Species, ROS oxidative stress can result in non-controlled oxidation and damage of cellular structures such as DNA, protein and membrane lipids.

Analysis of oil fraction: Antioxidant activity of Galloyl quinic derivatives isolated from Pistacia lentiscus leaves. Olubunmi AtolaniSunday OladoyeA.

Hexane, petroleum spirit, dichloromethane, ethyl acetate, methanol and ethanol used were analytical, while silica gel F and vanillin spray reagent were obtained from the chemical store of the Department of Chemistry, University of Ilorin, Nigeria.


The radical was protected from light.

Numerous epidemiological studies have suggested a protective role of afdicana polyphenols on human health Arts and Hollman, [ 5 ]. Aqueous extract of the bark of Kigelia africana reverses early testicular damage induced by methanol extract of Carica papaya. It is noteworthy that they were isolated from this source for the first time. Minecoside and verminoside, two new iridoid glucosides from Veronica officinalis L.

Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts

Antioxidant activities of Iranian Corn Silk. Tannins are generally known to be useful in the treatment of inflamed kigeliq ulcerated tissues and have remarkable activity in cancer prevention Ruch et al. Inhibition of activator protein-1, nf-k b, and mapks and induction of phase 2 detoxifying enzyme activity by chlorogenic acid. The pulverized plant material weighing g was extracted exhaustively with n-hexane at room temperature for five days.

Folk Medicines of Kurukshetra district Haryana. Results and Discussion Phytochemical screening The phytochemical analysis conducted on the K.

Recent studies have, however, stressed that the mechanisms of biological actions of polyphenols go beyond their ROS scavenging and metal chelating properties Halliwell et al. Phytol is an essential precursor to the synthesis of chlorophyll in plants De Souza and Nes, The current work led to isolation and characterization of nine constituents including iridoid glycosides, phenylpropanoid derivatives, and a eucommiol derivative.


Kigelia pinnata Lam Benth a species in the Bignoniaceae family commonly known as Kigelia africana is locally known as pandoro, uturubien and some other names based on their location in Nigeria and entire Africa Olatunji and Atolani, ; Oladele et al.

Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts

The chloroform extract exhibited substantial antileishmanial activity of Leishmania donovani. Prostaglandins Leukot Essent Fatty Acids. The mixture was centrifuged at g for 10 min to collect the africanq layer of the solution 2. Antimicrobial, antioxidant, and wound healing properties of Kigelia africana Lam.

New Constituents of Kigelia pinnata Leaves – SciAlert Responsive Version

Support Center Support Center. The methanol-extract was decanted, filtered and concentrated in vacuo to yield Kigelja spectrophotometric assay uses the stable radical 1,1-diphenylpicrylhydrazyl DPPH as a reagent Amarowicz et al. It is predicted that compound IV may be a precursor to the biosynthesis of phytol.

Meroterpenoids and naphthaquinones from Kigelia pinnata.

Thin layer chromatography, TLC plate were examined with a UV lamp operating at a wavelength of and nm. This study indicates that the ethyl acetate fraction of the plant root has high antioxidant activity against DPPH than the hexane and methanol extract.

Important heteronuclear multiple-bond correlations of compound 4 Click here to view.